What we are looking for

A research assistant/lab technician position is available in the team of “RNA Splicing in Cancer (RSC)” at the BioMed X Innovation Center in Heidelberg. Emerging data indicate that alterations in RNA splicing play a critical role in the pathogenesis of several molecular subtypes of cancer. Such alterations can lead to constitutive activity of oncogenes, reduced expression of tumor suppressors, or drug resistance. Team RSC is interested in identifying key molecular and cellular mechanisms for splicing abnormalities in cancer development, which could be exploited as potential targets for the treatment of multiple cancer subtypes. As part of the research project, novel therapeutic concepts are to be developed that explore the complex pathophysiology of tumor cells within human tissues, with a focus on oncogenic RNA splicing aberrations. The lab will employ high-throughput approaches combined with mechanistic cellular biology and in vitro/in vivo cancer models. We are looking for highly enthusiastic researchers to broaden our think-tank with her/his intellectual power and technical excellence. The ideal candidate would have a Master degree in oncology and/or RNA biology, and a strong background in cancer models.

Required skills

• Cancer cell models
• Primary tissue culture
• Hands-on experience in molecular biology techniques (cloning, PCR, RNA isolation, Western blotting, immunoprecipitation)
• Experience in lab management
• Very good work organization skills
• Ability to work in a milestone-driven environment
• Experienced to work in interdisciplinary teams
• Excellent communication skills in English

Additional preferred skills

• CRISPR/Cas genome editing
• FISH
• Fluorescence microscopy
• Viral gene delivery

Candidates are requested to submit

• 1-page cover letter explaining the reasons of interest to join our team
• Curriculum Vitae outlining scientific interests, research achievements, a record of publications, future personal goals and extra-scientific passions
• 2 reference letters

What we offer

The post is offered for an initial term of two years, with the possibility of prolongation for up to two additional years. BioMed X is a multidisciplinary and international research institution with a very collegial and flexible working environment. As part of the remuneration package we offer a competitive salary, access to training and lecture courses in house as well as in neighboring research institutions on the Life Science Campus in Heidelberg. Team recognition events, such as our annual two-day retreat, joint luncheons and after work events, a Summer and a Christmas party are just some of the other perks our fellows enjoy.

The position is sponsored by Merck.

The position is available immediately. Please submit your application until 20 March 2018 for the attention of Dr. Jan Mauer via the online application system on this website.